This will be fixed in ISE 14.1 software, but users can work around this issue bymanually setting top-level parameter "nCK_PER_CLK," as long they adhere to the frequency restrictions above.
Workaround:
Generate the design you need in 4:1 mode. Then, open up the top-level example_top.v or <user_design>.v and change the following parameter:
CK_PER_CLK = 2, //This changes the memory controller clock to DRAM clock ratio from 4 to 2