There are four files that need to be downloaded from http://www.xilinx.com/support/download/index.htm:
Xilinx_ISE_DS_14.3_P.40xc.1.0-1.tar (TAR/GZ - 2.782 GB)
Xilinx_ISE_DS_14.3_P.40xc.1.0-2.zip.xz (ZIP - 1.956 GB)
Xilinx_ISE_DS_14.3_P.40xc.1.0-3.zip.xz (ZIP - 1.852 GB)
Xilinx_ISE_DS_14.3_P.40xc.1.0-4.zip.xz( ZIP - 1.862 GB)
When they are all downloaded, untar the Xilinx_ISE_DS_14.3_P.40xc.1.0-1.tar file and then launch the xsetup.exe file.
On the second screen of the install it will ask for the you to select the location of the other three installation files.
After selecting the folder and then going to the next screen, the installer checks the integrity of the required install files.
Once the this integrity check is done you can continue to install as in a typical install.